Transformative Ketamine Therapy, From Home in Missouri
When traditional therapy or medication isn’t enough, ketamine therapy can offer a breakthrough. Our evidence-backed program combines at-home ketamine treatment with expert integration coaching to help address the root of depression, anxiety, PTSD, and more.
You deserve real relief
safely and comfortably
Our mission is to help you unlock healing and personal transformation, all from the safety and privacy of home. This is more than symptom management—it’s a path toward deeper wellness.
Video consultation with a licensed clinician
Guided preparation and integration coaching
All prescription and non-prescription medications included
Tailored psychedelic therapy for your unique needs
What’s included in our ketamine therapy program:
- Treatment for depression, anxiety, bipolar disorder, PTSD, and other emotional challenges
- Clinically proven, safe, and effective treatment plan
- Ketamine boosts neuroplasticity by increasing glutamate transmission—helping your brain create new, healthier pathways
- Improves synaptic connections to interrupt harmful thought loops
- Supports chronic pain relief by blocking excessive pain signals before they reach the brain
- Minimal short-term side effects, no known long-term risks
- Many people experience relief within hours—not weeks
- All from the comfort and privacy of your home
Anxiety
Depression
“I was really struggling with ruminating anxiety despite psychotherapy. My clinician made me feel comfortable… and the experience blew my mind. I’m finally out of the rut I was in for several years. I LOVE that feeling.”
Sofia S.
Frequently Asked Questions (FAQ)
We know that ketamine modulates additional receptor types, but the glutamate receptors seem to play the most important role in ketamine’s ability to treat depression and anxiety.
Neurons have a number of different binding sites for glutamate, but when it comes to ketamine, two are of particular interest: the NMDA receptor and the AMPA receptor.
By increasing the level of glutamate transmission while also shifting the balance of glutamate activation from NMDA to AMPA receptors, ketamine rapidly upregulates neuronal production and release of BDNF (brain-derived neurotrophic factor). Aptly called fertilizer for the brain, BDNF is a protein that helps promote the growth, maintenance, and survival of neurons—in other words, it enhances neuroplasticity.
The answer is often yes. Each person’s health profile is unique, and during your video consultation, a clinician will work with you to determine the best treatment plan based on your evaluation and health history. Some medications are contraindicated with ketamine, so please be sure to walk through your current medications with your clinician.
Some Impact clients have been able to safely taper off their anti-anxiety or antidepressant medications under the close supervision of their existing psychiatric providers, following improvements from ketamine therapy.
In addition to ketamine for anxiety, ketamine therapy is backed by research and used by Impact to treat depression.
Ketamine has also been used successfully to treat post-traumatic stress disorder (PTSD), OCD, chronic pain, and is an emerging treatment for other diagnoses.
Ketamine therapy has an excellent safety record.
Clinical team and board of expert advisors have decades of experience in psychiatry, psychedelic research, and ketamine treatment. The clinical protocols that they’ve implemented ensure that we’re providing safe and science-backed treatment for all of our clients.
Our expert clinicians are licensed, and Guides are equipped with experience and training to lead you safely through the entirety of your psychedelic therapy experience.
We have helped hundreds of clients achieve positive outcomes through ketamine therapy.
Using ketamine for depression treatment is 100% legal.
Currently, ketamine is the only legally prescribable psychedelic medicine available, and is available for off-label use for diagnoses like depression. Ketamine prescriptions are given exclusively through licensed clinicians.
